Research

| Biointerfaces | Biosensors |

A general overview of our research interests

  • Functional Genomics/Precision Medicine/Computational Biology

    • Sequence analysis

    • Protein structure modelling

    • Protein structure-function analysis

    • Protein-drug interaction/drug discovery/in silico docking

    • Molecular dynamics simulation/protein structural flexibility

  • Experimental Biology

    • Molecular Biology, Biochemical, Biophysical and Monolayer/Single Cell assays

    • Bioluminescence Resonance Energy Transfer (BRET) assays

    • Hybrid supported membrane-live cell assays/In vitro Reconstitution assays

  • Microscopy/Advanced Bioimaging

    • High-end fluorescence microscopy including

      • Total Internal Reflection by Fluorescence (TIRF)

      • Confocal/Spinning Disk Confocal microscopy

    • Label-free imaging/Reflection Interference Contrast Microscopy (RICM)

    • Single molecule imaging/Photoactivated Localization Microscopy

  • Materials Sciences/Microfabrication

    • Supported membrane assembly to mimic cell membrane environment

    • Nano- and micropatterned substrates

    • Multicomponent membrane microarray fabrication for spatially resolved receptor crosstalk studies in single cells