Research

| Biointerfaces | Biosensors |

A general overview of our research interests

  • Functional Genomics/Precision Medicine/Computational Biology
    • Sequence analysis
    • Protein structure modelling
    • Protein structure-function analysis
    • Protein-drug interaction/drug discovery/in silico docking
    • Molecular dynamics simulation/protein structural flexibility
  • Experimental Biology
    • Molecular Biology, Biochemical, Biophysical and Monolayer/Single Cell assays
    • Bioluminescence Resonance Energy Transfer (BRET) assays
    • Hybrid supported membrane-live cell assays/In vitro Reconstitution assays
  • Microscopy/Advanced Bioimaging
    • High-end fluorescence microscopy including
      • Total Internal Reflection by Fluorescence (TIRF)
      • Confocal/Spinning Disk Confocal microscopy
    • Label-free imaging/Reflection Interference Contrast Microscopy (RICM)
    • Single molecule imaging/Photoactivated Localization Microscopy
  • Materials Sciences/Microfabrication
    • Supported membrane assembly to mimic cell membrane environment
    • Nano- and micropatterned substrates
    • Multicomponent membrane microarray fabrication for spatially resolved receptor crosstalk studies in single cells

bioinformatics tools

BLAST | SMS2 | CLUSTAL O | PFAM | SMART | Expasy | SMILES | Autodock | General Tools |