MEmBERS

PRINCIPAl INVESTIGATOR

Dr. Kabir H Biswas

Dr. Biswas is broadly interested in designing biointerfaces and biosensors for the purpose of understanding and controlling cellular signaling with an emphasis on the role of spatial organization and mechanical regulation of signaling proteins. He employs a variety of biophysical and materials approaches including nano- and micropatterning techniques to design supported membrane-based patterned substrates and genetically encoded, bioluminescence resonance energy transfer (BRET)-based sensors. Traditional biochemical and cellular assays provide some understanding of cellular signaling including the identity of the proteins involved in a particular pathway, and their biochemical transformations or interacting partners. However, these techniques are often unsuitable for dissecting the role of the spatial organization or mechanical regulation of signaling proteins, features that have been recently revealed to be of prime importance. Some examples of such regulation include molecular mobility-dependent cadherin adhesion formation, spatial localization-dependent T-cell receptor signaling, and substrate rigidity-dependent integrin signaling. Insights gained from these studies will aid in the development of alternative, novel therapeutic avenues for diseases such as cancer.

Postdoctoral Fellow

[1] Dr. Anupriya M Geethakumari, CHLS, HBKU (Spring 2020 - )

Publications:

Moovarkumudalvan B, Geethakumari AM, Ramadoss R, Biswas KH and Mifsud B Biomolecules 2022, 12(12): 1754


Graduate students

Current


[5] Asma Fatima, PhD student, BBS, CHLS, HBKU (Fall 2022 - ongoing)

Publications:

   [Biorxiv - Preprint DOI: 10.1101/2022.01.31.478460]


[4] S M Nasiruddin, PhD student, BBS, CHLS, HBKU (Spring 2021 - ongoing)

Publications:

   [Biorxiv - Preprint DOI: 10.1101/2022.01.31.478460]


[3] Angelin Philip, PhD student, GPM, CHLS, HBKU (Fall 2020 - ongoing)

Publications:

Philip AM, Ahmed WS, Biswas KH* Computational and Structural Biotechnology Journal 2023 [Accepted]


[2] Asfia Sultana, PhD student, BBS, CHLS, HBKU (Fall 2020 - ongoing)

Publications:


Former

[1] Wesam Ahmed, PhD student, BBS, CHLS, HBKU (Spring 2020 - Spring 2023)

Publications:

   [Biorxiv - Preprint DOI: 10.1101/2022.01.31.478460]

Arshad N, Laurent-Rolle M, Ahmed WS, Hsu JC-C, Mitchell SM, Pawlak J, Sengupta D, Biswas KH, Cresswell P Proceedings of the National Academy of Sciences U S A 2022, 120(1): e2208525120

Philip AM, Ahmed WS, Biswas KH* Computational and Structural Biotechnology Journal 2023, 21: 1966

Jan Z, Ahmed WS, Biswas KH*, Jithesh PV* Journal of Biomolecular Structure & Dynamics 2023 [Accepted]

7Posifor graduate students to work on exciting projects related to mechanisms of cell signaling using a variety of biophysical and materials engineering approaches. Graduate students at HBKU who find our work interesting may get in touch with Dr. Biswas directly.

Masters students

Current


Former

[2] Asma Fatima, MS student, BBS, CHLS, HBKU (Fall 2021 - Spring 2022)

Publications:


[1] Saad Rasool, MS student, GPM, CHLS, HBKU (Fall 2020 - Fall 2021)

Publications:


Masters student at HBKU interested in our laboratory may write to Dr. Biswas directly.

ROTATION students

[5] Asfia Sultana, PhD student, BBS, CHLS, HBKU (Fall 2020)

[4] Debora Nicaretta Mattei, MS student, BBS, CHLS, HBKU (Fall 2020)

[3] Wesam Ahmed, PhD student, BBS, CHLS, HBKU (Fall 2019)

[2] Lutfiye Yildiz Ozer, PhD student, BBS, CHLS, HBKU (Fall 2019)

[1] Nada Mohamed Kafour, MS student, BBS, CHLS, HBKU (Fall 2019)

ALUMNI

[4] Debora Nicaretta Mattei, MS student (rotation), BBS, CHLS, HBKU (Fall 2020)

[3] Dr. Tausif Altamash, Postdoctoral Fellow, CHLS, HBKU (Fall 2019 - Spring 2020)

Publications:

[2] Lutfiye Yildiz Ozer, PhD student (rotation), BBS, CHLS, HBKU (Fall 2019)

[1] Nada Mohamed Kafour, MS student (rotation), BBS, CHLS, HBKU (Fall 2019)