Publications

Peer-Reviewed Publications

See also: Google Scholar Profile

* = corresponding author

# = equal contribution


37. SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to downregulate MHC-I surface expression

Arshad N, Laurent-Rolle M, Ahmed WS, Hsu JC-C, Mitchell SM, Pawlak J, Sengupta D, Biswas KH, Cresswell P*


Biorxiv – Preprint [DOI: 10.1101/2022.05.17.492198]


36. Structure-Based Virtual Screening and Functional Validation of Potential Hit Molecules Targeting the SARS-CoV-2 Main Protease


Moovarkumudalvan B, Geethakumari AM, Ramadoss R, Biswas KH and Mifsud B


Biomolecules 2022, 12(12), 1754

DOI: 10.3390/biom12121754


35. The Evolving Role of Extracellular Vesicles (Exosomes) As Biomarkers In Traumatic Brain Injury (TBI): Clinical Perspectives And Therapeutic Implications


Khan NA, Asim M, Menyer AE, Biswas KH, Rizoli S, Thani HA


Frontiers Aging Neuroscience 2022, 14: 933434


DOI: 10.3389/fnagi.2022.933434


34. A Genetically Encoded BRET-based SARS-CoV-2 Mpro Protease Activity Sensor

Geethakumari AM, Ahmed WS, Rasool S, Fatima A, Uddin SM Nasir, Aouida M, Biswas KH*

Communications Chemistry 2022, 5: 117

DOI: 10.1038/s42004-022-00731-2

Biorxiv - Preprint [DOI: 10.1101/2022.01.31.478460]


33. Patterned Substrate of Mobile and Immobile Ligands to Probe EphA2 Receptor Clustering

Chen Z, Biswas KH, Groves JT

Bio-protocol 2022, 12(11):

DOI: 10.21769/BioProtoc.4434


32. Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex

Ahmed W, Philip AM, Biswas KH*

Frontiers in Molecular Biosciences 2022, 9: 846996

DOI: 10.3389/fmolb.2022.846996

Stable Interaction of the UK B.1.1.7 lineage SARS-CoV-2 S1 Spike N501Y Mutant With ACE2 Revealed By Molecular Dynamics Simulation

Biorxiv - Preprint DOI: 10.1101/2021.01.07.425307


31. Understanding the mechanism of dysglycemia in a Fanconi-Bickel syndrome patient

Sharari S, Saifaldeen M, Mohammed I, Haris B, Bhat AA, Hawari I, Nisar S, Pavlovski I, Biswas KH, Almabrazi H, Syed N, Maacha S, Grivel JC, Aouida M, Ericsson J, Hussain K

Frontiers in Endocrinology 2022, 13: article 841788

DOI: 10.3389/fendo.2022.841788


30. Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2

Oh D #, Zhongwen C#, Biswas KH, Bai F, Sheetz MP, Groves JT

Biophysical Journal 2022, 121(10):1897-1908

DOI: 10.1016/j.bpj.2022.04.015


29. Gulf Cooperation Council Clinical Trials in the Pursuit of Medications for COVID-19

Jaber BA, Househ M, Shah Z, Rahman MS, Hamdi M, Biswas KH, Alam T

Informatics and Technology in Clinical Care and Public Health 2022, 9

DOI: 10.3233/SHTI210846


28. Probe the Effect of Clustering on EphA2 Receptor Signaling Efficiency by Subcellular Control of Ligand-Receptor Mobility

Chen Z, Oh D, Biswas KH*, Zaidel-Bar R*, Groves JT*

eLife 2021, 10:e67379

DOI: 10.7554/eLife.67379


27. Intracellular Ionic Strength Sensing Using NanoLuc Bioluminescence

Altamash T, Ahmed W, Rasool S, Biswas KH*

International Journal of Molecular Sciences 2021, 22(2), 677

DOI: 10.3390/ijms22020677


26. Phosphodiesterase 5: Protein Structure, Regulation of Activity, Mechanism of Inhibition, and Therapeutic Applications of Inhibitors

Ahmed W, Geethakumari AM, Biswas KH*

Biomedicine and Pharmacotherapy 2021, 134: 111128

DOI: 10.1016/j.biopha.2020.111128 [Invited Review Article]


25. Role of actin cytoskeleton in E-cadherin-based cell-cell adhesion assembly and maintenance

Rasool S#, Geethakumari AM#, Biswas KH*

Journal of the Indian Institute of Science 2021, 101(1): 51-62

DOI: 10.1007/s41745-020-00214-0 [Invited Review Article]


24. Molecular mobility-mediated regulation of E-cadherin adhesion

Biswas KH*

Trends in Biochemical Sciences 2020, 45(2): 163-73

DOI: 10.1016/j.tibs.2019.10.012 [Invited Review Article]


23. A Molecular Assembly Phase Transition and Kinetic Proofreading Modulate Ras Activation by SOS

Huang WYC, Alvarez S, Kondo Y, Lee YK, Chung JK, Lam HYM, Biswas KH, Kuriyan J, Groves JT

Science 2019, 363(6431): 1098-1103 [PDF]

DOI: 10.1126/science.aau5721


22. Hybrid Live Cell-Supported Membrane Interfaces for Signaling Studies

Biswas KH*, Groves JT*

Annual Review of Biophysics 2019, 48: 537-62 [PDF]

DOI: 10.1146/annurev-biophys-070317-033330 [Invited Review Article]

Invited review article


21. Membrane Reconstitution of Monoamine Oxidase Enzymes on Supported Lipid Bilayers

Wang L#, Biswas KH#, Kawakami L, Park S, Yoon BK, Cho N-J

Langmuir 2018, 34(36): 10764-73 [PDF]

DOI: 10.1021/acs.langmuir.8b01348


20. Fabrication Of Multicomponent, Spatially Segregated DNA And Protein Functionalized SupportedMembrane Microarray

Biswas KH*, Cho N-J, Groves JT*

Langmuir 2018, 34(33): 9781-8 [PDF]

DOI: 10.1021/acs.langmuir.8b01364


19. Spatially modulated ephrinA1:EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility

Zhongwen C#, Oh D#, Biswas KH, Yu C-H, Zaidel-Bar R, Groves JT

Proceedings of the National Academy of Sciences U S A 2018, 115(25): E5696-E5705 [PDF]

DOI: 10.1073/pnas.1719961115


18. Regulation of α-catenin conformation at cadherin adhesions

Biswas KH*

Journal of Biomechanical Science & Engineering 2018, 13(4):17-00699 [PDF]

DOI: 10.1299/jbse.17-00699 [Invited Review Article]


17. Multicomponent Supported Membrane Microarray for Monitoring Spatially Resolved Cellular Signaling Reactions

Biswas KH*, Zhongwen C, Dubey AK, Oh D, Groves JT*

Advanced Biosystems 2018, 2(4): 1800015 [PDF]

DOI: 10.1002/adbi.201800015


16. Interfacial forces dictate pathway of phospholipid vesicle adsorption and spontaneous rupture onto silicon dioxide surfaces

Biswas KH, Jackman JA, Park JH, Groves JT, Cho NJ

Langmuir 2018, 34(4), 1775-82 [PDF]

DOI: 10.1021/acs.langmuir.7b03799


15. Spatial and mechanical aspects of signal transduction in the cell membrane

Biswas KH*, Groves JT*

In: Bassereau P., Sens P. (eds) Physics of Biological Membranes. Springer, Cham, 2018, 537-60 (Book chapter) [PDF]

DOI: 10.1007/978-3-030-00630-3_19 [Invited Book Chapter]


14. Buffer NaCl concentration regulates Renilla luciferase activity and ligand-induced conformational changes in the BRET-based PDE5 sensor

Biswas KH*, Viswesweriah SS*

Matters 2017 [PDF]

DOI: 10.19185/matters.201702000015


13. Dynamic cellular interactions with extracellular matrix triggered by biomechanical tuning of low-rigidity, supported lipid membranes

Vafaei S, Tabaei SR, Biswas KH, Groves JT, Cho NJ

Advanced Healthcare Materials 2017, 6(10): 1700243-n/a [PDF]

DOI: 10.1002/adhm.201700243


12. Early events in the assembly of E-cadherin adhesions

Biswas KH* and Zaidel-Bar R*

Experimental Cell Research 2017, 358(1): 14-9 [PDF]

DOI: 10.1016/j.yexcr.2017.02.037 [Invited Review Article]


11. Allosteric regulation of proteins: a historical perspective on the development of concepts and techniques

Biswas KH*

Resonance 2017, 22(1): 37-50 [PDF]

DOI: 10.1007/s12045-017-0431-z


10. Sustained α-catenin activation at E-cadherin junctions in the absence of mechanical force

Biswas KH*, Hartman KL, Zaidel-Bar R*, Groves JT*

Biophysical Journal 2016, 111: 1044-52 [PDF]

DOI: 10.1016/j.bpj.2016.06.027

See also:

Force Bistability in Adhesion Switch

F1000Prime recommendation


9. A microbead supported membrane-based fluorescence imaging assay reveals intermembrane receptor-ligand complex dimension with nanometer precision

Biswas KH*, Groves JT*

Langmuir 2016, 32(26): 6775–80 [PDF]

DOI: 10.1021/acs.langmuir.6b01377


8. Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

Yu C-h, Rafiq NBM, Cao F, Zhou Y, Krishnasamy A, Biswas KH, Ravasio A, Chen Z, Wang Y-H, Kawauchi K, Jones GE, Sheetz MP

Nature Communications 2016, 6:8672 [PDF]

DOI: 10.1038/ncomms9672


7. E-cadherin junction formation involves an active kinetic nucleation process

Biswas KH#, Hartman KL#, Yu C-h, Harrison OJ, Song H, Smith AW, Huang WYC, Lin W-C, Guo Z, Padmanabhan A, Troyanovsky SM, Dustin ML, Shapiro L, Honig B, Zaidel-Bar R, Groves JT

Proceedings of the National Academy of Sciences U S A 2015, 112(35):10932-7 [PDF]

DOI: 10.1073/pnas.1513775112

See also:

E-cadherin mobility regulates adhesion formation


6. Cyclic nucleotide binding and structural changes in the isolated GAF domain of Anabaena adenylyl cyclase, CyaB2

Biswas KH*, Badireddy S, Rajendran A, Anand GS and Viswesweriah SS*

PeerJ 2015, 3:e882; DOI 10.7717/peerj.882 [PDF]

DOI: 10.7717/peerj.882


5. Familial Diarrhea Syndrome Caused by an Activating GUCY2C Mutation

Finkerstrand T, Arshad N, Haukanes BI, Tronstad RR, Pham KDC, Johansson S, Havik B, Tonder SL, Levy SE, Brackman D, Boman H, Biswas KH, Apold J, Hovdenak N, Visweswariah SS and Knappskog PM

New England Journal of Medicine 2012, 366(17):1586-95 [PDF]

DOI: 10.1056/NEJMoa1110132

See also:

Familial diarrhea syndrome

Genetic mutation found in familial chronic diarrhea syndrome

Chromosome 12 Mutation Linked to Familial Diarrhea

GUCY2C gene mutation leads to familial diarrhea syndrome

Gene May Play Role in Frequent Diarrhea


4. Distinct Allostery Induced in the Cyclic GMP-binding, Cyclin GMP-specific Phosphodiesterase (PDE5) by Cyclic GMP, Sildenafil and Metal Ions

Biswas KH and Visweswariah SS

Journal of Biological Chemistry 2011, 286(10): 8545-54 [PDF]

DOI: 10.1074/jbc.M110.193185


3. The Linker Region in Receptor Guanylyl Cyclases is a Key Regulatory Module: Mutational Analysis of Guanylyl Cyclase C

Saha S, Biswas KH, Kondanapallic C, Isloor N and Visweswariah SS

Journal of Biological Chemistry 2009, 284(40): 27135-45 [PDF]

DOI: 10.1074/jbc.M109.020032s


2. The Evolution of Guanylyl Cyclases as Multidomain Proteins: Conserved Features of kinase-cyclase domain fusions

Biswas KH, Shenoy AR, Dutta A and Visweswariah SS

Journal of Molecular Evolution 2009, 68(6):587-602 [PDF]

DOI: 10.1007/s00239-009-9242-5


1. The GAF Domain of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) is a sensor and a sink for cGMP

Biswas KH, Sopory S and Visweswariah SS

Biochemistry 2009, 47(11): 3534-43 [PDF]

DOI: 10.1021/bi702025w

Non-peer Reviewed Publications

7. Vaccine Doses: A Changing Medical Approach

TRT World | TRT Arabic | HBKU


6. Will mutations cause the weakening of coronavirus making it fade and disappear?

Al Jazeera Arabic


5. Vaccination is Vital Not Only for Individual Health but Also to Thwart the Pandemic

CHLS/HBKU


4. Review 1: " Neutralization of N501Y mutant SARS-CoV-2 by BNT162b2 vaccine-elicited sera"

Rapid Reviews: COVID-19


3. Oped: Tackling Childhood Asthma: the View from Qatar

Qatar Tribune | Gulf Times | The Peninsula | MENAFN


2. Oped: Why Scepticism is Integral to Science, But Not All of it is Good

Silicon Republic


1. Oped: How Dogs Could Help In Detecting COVID-19 Carriers In The Future

Qatar Tribune | Gulf Times;