Cell adhesion & Signaling lab
| Precision Medicine | Biointerfaces | Biosensors | Microfabrication | Cellular Adhesion & Signaling | Membranes | Imaging | Protein Structure-Function Analysis | Bioinformatics |
Welcome!
We utilize state-of-the-art computational tools including deep learning-based methods for protein structure prediction and molecular dynamics simulations to design and understand proteins for therapeutic applications and drug discovery, specifically targeting infectious diseases, cardiovascular diseases, and cancer metastasis.
Research in our laboratory is funded through CHLS/HBKU internal fund, HBKU Innovation Center, Office of the Vice President of Research, and the Qatar National Research Foundation (QNRF).
In the news:
Grants
1st November 2023 - Dr. Biswas (LPI; with Dr. Mustapha Aouida/CHLS, Dr. Prasanna Kolatkar/QBRI, and Dr. Hebah Al-Khatib/Qatar University) receives major funding (Academic Research Grant - Cycle 01) from Qatar Research Development and Innovation Council (QRDI)/Qatar National Research Foundation (QNRF)! We will be studying SARS-CoV-2 proteases with innovative biosensors to identify dual protease inhibitors.
Dr. Biswas received funding from the HBKU Innovation Center (Industrial Innovation Fund - Cycle 06) for developing a cGMP biosensor with an extended dynamic range of detection!
15th December 2022 - Biswas lab, in collaboration with Dr. Prasanna Kolatkar and Dr. Henning Horn, received the HBKU Thematic Grant Cycle 02 fund! We will be utilizing state-of-the-art deep learning-based computational tools, in conjunction with bioluminescence-based biosensors and other biophysical and cell-based assays to design and characterize synthetic peptide-based PROTACS that bind and cause degradation of alpha-catenin for potential application in abrogating metastasis of breast cancer cells that utilize cadherin adhesion for homing to new organs.
Happy to announce that we have received the HBKU IC Industrial Innovation Fund 2022
Delighted to announce we have been awarded the Rapid Response Call (RRC) Covid-19: Lessons Learned and Road to Recovery grant with Dr. Tanvir Alam/CSE (LPI)!
Glad to announce that we have received the HBKU IC Industrial Innovation Fund 2021
Awards/Prizes
17th October 2023 - Angelin & team was awarded the first position in the Young Investigator Awards at the 4th International Computational Science and Engineering Conference (ICSEC23)!
26th Sept 2022 - Dr. Anu received the Best Poster Award at the Precision Medicine & Functional Genomics conference organized by Sidra Medicine, Doha, Qatar!
Other Achievements
* Cadherin adhesion on a membrane
(Biswas et al, PNAS 2015) * Lipid exchange between membranes
(Biswas et al, Adv Biosys 2018)| Qatar Foundation | HBKU | CHLS | Biswas/CHLS/HBKU | Google | Google Scholar | Pubmed | PDB | Twitter | LinkedIn |